Research Interests

Dr. Kwentus’ work has focused primarily on project feasibility, milestones, and methodology. He has worked on projects in all age categories including geriatric and pediatric populations. Previous protocol design and strategic planning activities included postoperative pain, chronic pain management, acute stroke, dementia, cognitive disorders, schizophrenia, affective disorders, and other major psychiatric disorders. Dr. Kwentus has had primary responsibility for an expert panel authoring a protocol and has participated in protocol development on 12 multicenter projects. He has conducted 12 investigator rating scales training sessions and presented the protocol at 8 investigator meetings. He has participated in project start up meetings for 20 multicenter projects. Responsibilities have included CRA support and training, medical monitoring, and data base review. Dr. Kwentus has specialized in patient recruitment and has consulted individually with investigators and personally visited over 50 research sites.

Selected Publications

Kwentus, J.A., Sheffel, W.S.: The use of disulfiram and naltrexone. In Lerner, W.D., Barr, M.A. (ed.), Handbook of Hospital Based Substance Abuse Treatment, Pergamon Press: 154-168, 1990.

Harkins S., Kwentus, J.A.: Pain, suffering, and discomfort in the elderly. In Bonica, J.J. (ed.) Management of Pain, second edition, Lea & Feliger: 552-561, 1990.

Kehoe, W.A., Harralson, A.F., Kwentus, J.A., Jacisin, J.J., Scheffel, W.B.: Early individualization of tricyclic antidepressant dosing using a bayesian pharmacokinetic model. DICP: The Annals of Pharmacotherapy, 25: 1368-1374 1991.

Kehoe, W.A., Kwentus, J.A., Scheffel, W.B., Harralson, A.F.: Alpha-1-acid glycoprotein plasma concentrations in psychiatric patients: A cause of low free imipramine concentrations early in therapy. Biologic Psychiatry, 29: 489-493 1991.

Kwentus, J.A.: Alzheimer's Disease: In Kiple, K.F. (ed) The Cambridge World History of Human Disease, Cambridge Press: 561-567, 1993.

Hart, R.B., Kwentus, J.A.: Memory disorder and behavior in survivors of Herpes Simplex Encephalitis: In Neurotoxicology.

Goyer, P., Kwentus, J.A.: Basic science of neuroimaging and potential applications for consultation-liaison psychiatry. In Rundell, J.R., Wise, M.G. (ed) Textbook of Consultation-Liaison Psychiatry, American Psychiatric Press, 1996.

Margolin, R., Kwentus, J.A.: Surgery in the older psychiatric patient. In Adkins, R.B., Scott, H.W., Surgical Care for the Elderly, Lippencott Raven: 131-150, 1997.

Kennedy, J.S., Kwentus, J.A., Kumar, V., Schmidt, D.: Cholinergic system therapy for Alzheimer's Disease: In Kumar, V., Eisdofer, C., Advances in the Diagnosis and Treatment of Alzheimer's Disease, Springer: 455-510, 1998.

Kwentus, J.A., Kathol, R.G.: Integrierte medizinische und psychiatrische stationen und behandlumngskonzepte - implementierung eines neuen versorgungsmodells: In Diefenbacher A Aktuelle Konsiliarpsychiatrie und – psychotherapie Thieme, 161-176, 1999.

Kwentus, J.A.: Integrated inpatient medicine and psychiatric services. The Economics of Neuroscience, 1: 61-65, 1999.

Kwentus, J.A., Reiner, S.M., Banks, D., Surber, R.: Integrated inpatient medicine and psychiatric services. Primary Psychiatry 6: 73-80, 1999.

Kwentus, J.A.: Delirium, dementia, & amnestic syndromes. In Ebert, M.H., Loosen, P.T., Nurcombe, B.: In Current Diagnosis & Treatment in Psychiatry, McGraw Hill, 321-354, 2000.

Salomon, R.M., Kennedy, J.S., Johnson, B.W., Schmidt, D.E., Kwentus, J.A., Gwirtsman, H.E., Ebert, M.H.: Association of a critical CSF tryptophan threshold level with depressive relapse. Neuropsychopharmacology, May 28:5, 956-60, 2003.