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Mark C. Austin, Ph.D. Molecular Biology Core Director The University of Mississippi Medical Center Jackson, Mississippi Contact Dr. Austin |
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Core Personnel
Dharmendra Goswami, Ph.D., Postdoctoral Fellow Tina Smith, Researcher III |
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Over the past decade, the application of molecular biological techniques to the study of the central nervous system has revolutionized our thinking about synaptic transmission, neuronal plasticity, and neuronal integration, as well as the molecular basis of psychiatric illnesses. The center's Molecular Biology Core emphasizes the application of biotechnologically advanced molecular techniques to study the expression, structure, function, and localization of a variety of neural substrates in the brain. The Molecular Biology Core provides training, consultation, and technical assistance in molecular biological approaches that allow individual researchers to study various molecular endpoints, regulatory mechanisms, as well as the role of transcriptional and translational processes in regulating and controlling the expression of the various neural substrates of interest.
Dr. Mark Austin, Core Leader of the Molecular Biology Core, is a molecular neuropharmacologist with expertise in utilizing various molecular biological approaches to study the regulation of gene expression of neurotransmitter enzymes, receptors, transporters and neuropeptides.
The Molecular Biology Core provides shared-access to the following amplification, visualization, detection and analysis systems:
- Arcturus Veritas Laser Capture Microdissection System
- MyiQ Single-Color Real-Time PCR Detection System with SW/Beacon Designer Cycler IQ software
- BioRad Gel Documentation System
- BioRad Chemidoc XRS System
- BioTek FLx800 microplate fluorescence reader
- NanoDrop ND-1000A UV-Vis Spectrophotometer (1-2 5l samples)
- MCID Elite Image analysis system with Zeiss Axioskop Microscope and Ludl motorized stage
- Veritas Microplate Luminometer
- Bio-Rad Thermal cycler
- BioRad Real-Time PCR Machine
- BioRad PROTEAN isoelectric focusing system
- Hybaid Maxi-14 hybridization oven
- Eppendorf Multiporator for eukaryotic cells, bacteria and yeast
- Ependorf refrigerated microcentrifuge
- Zeiss Axioskop Digital Photomicroscopy Workstation
- GeneQuant RNA/DNA calculator
- Packard Scintillation Counter
- Leica Cryostat
The Molecular Biology Core serves as a central resource that enables, stimulates and facilitates the use of molecular biological approaches and further enhances the methodological diversity of Center Investigators as well as other departmental faculty.
